Twentyone Hotel, Rome

Book on our site
Up to 10% cheaper
than Booking.com
Check rooms and rates
From82US$ /night
Check-in
11Mar2026Select date
Check-out
12Mar2026Select date
Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

Via Cola Di Rienzo 23, Rome, Italy, 00192
Great
8.3
8.1
/10
3.5
3.7
/5

Twentyone Hotel, a modern 4-star hotel in Rome, features 93 elegant rooms designed with attention to detail. Notable amenities include the on-site restaurant Bistrò 21, offering a selection of traditional Italian cuisine, and a 24-hour reception. The hotel is situated in the Prati district, providing easy access to key attractions.

Rooms & Amenities

The rooms at Twentyone Hotel are furnished with custom-made designer furniture, offering amenities such as an LCD TV, minibar, and free WiFi. Guests can choose from various accommodations including deluxe double rooms with private terraces and junior suites featuring a Jacuzzi. Each room is equipped to meet modern needs and ensure a comfortable stay.

Dining Options

Bistrò 21 serves a variety of traditional Italian dishes for lunch and dinner, with a changing menu that includes gnocchi, fish, and meat options based on the day of the week. The restaurant also offers aperitifs and an ample buffet for guests seeking a casual dining experience before exploring the city.

Leisure & Activities

For leisure, Twentyone Hotel provides easy access to major landmarks such as the Vatican Museums, Spanish Steps, and Piazza Navona within walking distance. Public transport is accessible via the Lepanto Metro Station, located 400 meters from the hotel. Guests can also explore nearby parks like Villa Borghese, perfect for outdoor activities.

Services & Security

Services at Twentyone Hotel include a 24-hour reception to assist guests with inquiries or arrangements. The hotel features security systems for guest safety, ensuring a secure environment during their stay. With its central location and modern facilities, the hotel caters to both leisure and business travelers.

View all

Select your room type

Twentyone Hotel offers a variety of rooms including double rooms, family rooms, and suites with breakfast, free cancelations, and special deals
Triple Room
2 persons
240 sq. feet 
3 Single beds
Shower
Heating
Twin Room
2 persons
195 sq. feet 
2 Single beds
Shower
Heating
Family Room
2 persons
315 sq. feet 
1 King-size bed
Shower
Heating
Double Room
2 persons
195 sq. feet 
1 King-size bed
Shower
Heating
Click button to see more rooms
Show all rooms
Show all roomsLess

Price and Room Availability Calendar

Check availability and prices for your dates now!

Facilities

Twentyone Hotel offers amenities for your comfortable stay and unforgettable experiences
Facilities: Great
8.2/10Review score

General

  • Non-smoking rooms
  • Wi-Fi
  • Parking
  • Safe deposit box
  • 24-hour reception
  • Express check-in/ -out
  • No pets allowed
  • Rooms/ Facilities for disabled
  • Wheelchair access
  • Security
  • Luggage storage
  • Allergy-free rooms
  • Lift
  • Barber shop
  • Coffee shop
  • Smoke detectors
  • Electric vehicle charging station
  • Fire extinguishers
  • Key card access

Sports & Fitness

  • Fitness centre

Services

  • Paid airport shuttle
  • Room service
  • Housekeeping
  • Laundry
  • Dry cleaning
  • Tours/Ticket assistance
  • Welcome drink

Dining

  • In-room breakfast
  • Restaurant
  • Snack bar
  • Bar/ Lounge area
  • Packed lunches
  • Special diet menus

Business

  • Fax/Photocopying

Children

  • Cots
  • Children's buffet

Facilities for people with disabilities

  • Toilet for disabled
  • Bathroom for disabled

Spa & Leisure

  • Garden area
  • Leisure/ TV room

Room features

  • Air conditioning
  • Heating
  • Mini-bar
  • Soundproofed rooms
  • Sitting area
  • Terrace
  • Garden furniture
  • Tea and coffee facilities
  • Ironing facilities

Bathroom

  • Free toiletries
  • Sink

Media

  • Flat-screen TV
  • AM/FM alarm clock

Room decor

  • Carpeted floor
Show more

Twentyone Hotel Location

Via Cola Di Rienzo 23, Rome, Italy, 00192
Map view
Via Cola Di Rienzo 23, Rome, Italy, 00192
Nearby
Bridge
Castel Sant'Angelo
3500 ft
Square
Piazza del Popolo
2500 ft
Bridge
St. Angelo Bridge
3600 ft
Church
Church of Santa Maria del Popolo
2300 ft
Church
Basilica of Sant' Agostino
3400 ft
Restaurants
Bistro' 21
100 ft
Via Cola di Rienzo 23 Hotel Twenty One
Cantieri Bistrot
300 ft
Via Cola di Rienzo 16
Le Sicilianedde
300 ft
Via Cola di Rienzo
La Pinseria Prati
300 ft
Via Lucrezio Caro 60
Pasticceria Sanzini
500 ft
Via Valadier
VINO e FOCACCIA
500 ft
Piazza Cola di Rienzo 83/A
Grotta Azzurra
700 ft
Via Cicerone 62a
Quelli del bar Cicerone
600 ft
Via Cicerone 68
Ristorante Visconti 2.0
800 ft
Via Ennio Quirino Visconti 83
Getting around
City Centre
Rome28 min  ·  1.4 mi
Airports
Rome Ciampino Airport (CIA)28 min  ·  11.6 mi
Roma-Fiumicino Airport (FCO)45 min  ·  18.4 mi
Train
Flaminio Train Station10 min  ·  2700 ft
Underground
Lepanto Metro Station5 min  ·  1400 ft
Want to see Exclusive Early Booking Rate?
Get exlusive rates right now!
Check Rates
Property information and rules
Check-in
from 15:00-23:59
Check-out
from 07:00-11:00
Guest Parking
Private parking is possible on site (reservation might be needed) at EUR 35 per day.
Internet
Wireless internet is available in for free.
Breakfast
The hotel Twentyone provides visitors with a free full breakfast. 
Children & extra beds
There are no cots provided in a room. 
Pets
Pets are not allowed.
Languages
English, German, Spanish, Italian, Russian, Moldovan
Year renovated:
2009
Number of floors:
6
Number of rooms:
88

Reviews and Ratings

Feedback about Twentyone Hotel from previous guests about their experience.
Review score
Based on 1343 verified reviews
8.0/10
Great
85%
Recommend
Breakfast
8.4/10
Cleanliness
8.6/10
Comfort
8.5/10
Facilities
8.2/10
Free Wi-Fi
8.1/10
Location
9.1/10
Paid Wi-Fi
7.9/10
Staff
8.7/10
Value for money
7.8/10
Guest reviews
based on 1904 reviews
4/5
based on 3716 reviews
8.3/10
No reviews yet on our siteUnfortunately, our guests have not yet left any reviews for this hotel, but you can read reviews from Booking.com.
Open reviews

Next best alternative

Consider them for your next trip.
Check-in
11Mar2026Select date
Check-out
12Mar2026Select date
Rooms and Guests2 Guests, 1 Room