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Twentyone Hotel
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Twentyone Hotel, Rome

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Check rooms and rates
From82US$ /night
Check-in
24Jan2026Select date
Check-out
25Jan2026Select date
Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

Via Cola Di Rienzo 23, Rome, Italy, 00192
Great
8.3
8.1
/10
3.5
3.7
/5
“Situated just over the bridge from Piazza del Popolo, the hotel's location provides easy access to Rome's vibrant attractions and charming neighborhoods.”view full review

Twentyone Hotel is a modern 4-star hotel offering picturesque views of St. Peter's Dome and is characterized by sophisticated decor and a family atmosphere. It features an on-site restaurant, Bistrò 21, serving traditional Italian cuisine and various amenities for both leisure and business travelers.

Rooms & Facilities

The 93 elegant rooms at Hotel Twentyone combine custom-made designer furniture and modern conveniences, including free WiFi and LCD TVs. Deluxe double rooms on the fifth floor include a private terrace with views of the city's major monuments, while junior suites come with Jacuzzis for added luxury.

Dining Options

Bistrò 21 is the hotel's restaurant, offering daily traditional Italian dishes and an extensive selection of wines. The menu features daily changes, such as gnocchi on Monday and fish on Tuesday, along with an afternoon buffet available for lunch.

Location & Nearby Attractions

Hotel Twentyone provides easy access to Rome's major attractions, conveniently situated between the Vatican Museums and the Spanish Steps. Guests can explore notable sites such as St. Peter's Basilica, Trevi Fountain, and Villa Borghese, all reachable on foot or via nearby public transportation options.

Services & Transportation

The hotel offers 24-hour reception and concierge services, ensuring a comfortable stay. Guests can also utilize the Lepanto Metro Station, located just a 350-meter walk away, for efficient urban travel.

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Select your room type

The hotel offers a variety of rooms including double rooms, family rooms, and suites with breakfast, free cancelations, and special deals
Triple Room
Triple Room
2 persons
240 sq. feet 
3 Single beds
Shower
Heating
room details
Twin Room
Twin Room
2 persons
195 sq. feet 
2 Single beds
Shower
Heating
room details
Family Room
Family Room
2 persons
315 sq. feet 
1 King-size bed
Shower
Heating
room details
Double Room
Double Room
2 persons
195 sq. feet 
1 King-size bed
Shower
Heating
room details
Click button to see more rooms
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Price and Room Availability Calendar

Check availability and prices for your dates now!

Facilities

The hotel offers amenities for your comfortable stay and unforgettable experiences
Delicious Breakfast!
“I thoroughly enjoyed the breakfast buffet that offered a good mix of American classics and Italian specialties. The variety was impressive!” view full review
Comfortable and Modern!
“Our room was impeccably clean and equipped with modern amenities. The comfortable bed and excellent shower made our stay truly enjoyable.” view full review
Accessible Amenities
“The hotel's shower facilities were well-designed and easy to use, ensuring a comfortable experience for everyone.” view full review
Impressive Shower!
“The shower had amazing water pressure and provided a luxurious experience that made getting ready in the morning a pleasure.” view full review

General

  • Non-smoking rooms
  • Free Wi-Fi
  • On-site car park
  • Safe deposit box
  • 24-hour reception
  • Express check-in/ -out
  • No pets allowed
  • Rooms/ Facilities for disabled
  • Wheelchair access
  • Security
  • Luggage storage
  • Allergy-free rooms
  • Lift
  • Barber shop
  • Coffee shop
  • Smoke detectors
  • Electric vehicle charging station
  • Fire extinguishers
  • Key card access

Sports & Fitness

  • Fitness centre

Services

  • Paid airport shuttle
  • Room service
  • Housekeeping
  • Laundry
  • Dry cleaning
  • Tours/Ticket assistance
  • Welcome drink

Dining

  • In-room breakfast
  • Restaurant
  • Snack bar
  • Bar/ Lounge area
  • Packed lunches
  • Special diet menus

Business

  • Fax/Photocopying

Children

  • Cots
  • Children's buffet

Facilities for people with disabilities

  • Toilet for disabled
  • Bathroom for disabled

Spa & Leisure

  • Garden area
  • Leisure/ TV room

Room features

  • Air conditioning
  • Heating
  • Mini-bar
  • Soundproofed rooms
  • Sitting area
  • Terrace
  • Garden furniture
  • Tea and coffee facilities
  • Ironing facilities

Bathroom

  • Free toiletries
  • Sink

Media

  • Flat-screen TV
  • AM/FM alarm clock

Room decor

  • Carpeted floor
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Location

Via Cola Di Rienzo 23, Rome, Italy, 00192
Map view
Via Cola Di Rienzo 23, Rome, Italy, 00192
City landmarks
Fountain
Trevi Fountain
1.1 mi
Church
Pantheon
5200 ft
Square
Colosseum
1.8 mi
Landmark
Piazza Navona
4400 ft
Museum
Vatican Museums
1.0 mi
Church
St. Peter's Basilica
1.1 mi
Square
Saint Peter's Square
4900 ft
Landmark
Roman Forum
1.5 mi
Landmark
Piazza di Spagna
4500 ft
Square
Spanish Steps
5000 ft
Bridge
Castel Sant'Angelo
3500 ft
Square
Piazza del Popolo
2500 ft
Square
Piazza Venezia
1.3 mi
Church
Sistine Chapel
1.1 mi
Cemetery
Altar of the Fatherland
1.4 mi
Square
Campo de' Fiori
1.1 mi
Landmark
Vatican City
1.1 mi
Museum
Borghese Gallery and Museum
1.5 mi
Bridge
St. Angelo Bridge
3600 ft
Landmark
Torre di San Giovanni
1.6 mi
Church
Church of Saint Louis the French
4500 ft
Square
Largo di Torre Argentina
1.1 mi
Church
Church of Santa Maria del Popolo
2300 ft
Zoo
Bioparco di Roma
1.3 mi
Church
Santa Maria in Trastevere
1.4 mi
Museum
Capitoline Museums
1.3 mi
Square
Piazza Barberini
1.1 mi
Museum
Museum of the Ara Pacis
3000 ft
Square
Pincian Hill
3200 ft
Church
Church of the Gesu
1.2 mi
Nearby
Bridge
Castel Sant'Angelo
3500 ft
Square
Piazza del Popolo
2500 ft
Bridge
St. Angelo Bridge
3600 ft
Church
Church of Santa Maria del Popolo
2300 ft
Church
Basilica of Sant' Agostino
3400 ft
Restaurants
Bistro' 21
100 ft
Via Cola di Rienzo 23 Hotel Twenty One
Cantieri Bistrot
300 ft
Via Cola di Rienzo 16
Le Sicilianedde
300 ft
Via Cola di Rienzo
La Pinseria Prati
300 ft
Via Lucrezio Caro 60
Pasticceria Sanzini
500 ft
Via Valadier
VINO e FOCACCIA
500 ft
Piazza Cola di Rienzo 83/A
Grotta Azzurra
700 ft
Via Cicerone 62a
Quelli del bar Cicerone
600 ft
Via Cicerone 68
Ristorante Visconti 2.0
800 ft
Via Ennio Quirino Visconti 83
Getting around
City Centre
Rome28 min  ·  1.4 mi
Airports
Rome Ciampino Airport (CIA)28 min  ·  11.6 mi
Roma-Fiumicino Airport (FCO)45 min  ·  18.4 mi
Train
Roma San Pietro Train Station23 min  ·  1.2 mi
Underground
Lepanto Metro Station5 min  ·  1400 ft
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Property information and rules
Check-in
from 15:00-23:59
Check-out
from 07:00-11:00
Guest Parking
Private parking is possible on site (reservation might be needed) at EUR 35 per day.
Internet
is available in for free.
Breakfast
The hotel Twentyone provides visitors with a free full breakfast. 
Children & extra beds
There are no cots provided in a room. 
Pets
Pets are not allowed.
Languages
English, German, Spanish, Italian, Russian, Moldovan
Year renovated:
2009
Number of floors:
6
Number of rooms:
88

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Check-in
24Jan2026Select date
Check-out
25Jan2026Select date
Rooms and Guests2 Guests, 1 Room
  • Overview
  • Rooms
  • Price calendar
  • Facilities
  • Location
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